
Pesto grilled cheese sandwiches are a simple way to turn an ordinary lunch into something unforgettable Rich pesto creamy mozzarella and sharp cheddar all melt together between golden slices of bread delivering comfort and vibrance in each bite This is the grilled cheese I turn to when I want something cozy but just a bit gourmet It comes together so quickly that I often make it for a weeknight dinner when life gets hectic
This sandwich became a favorite for my husband and me during late-night movie nights Its gooey center and crispy edges never disappoint and we now keep pesto in the fridge just for this recipe
Ingredients
- Thick-cut bread: such as sourdough or Italian This holds up beautifully to the weight of the pesto and gooey cheese For the best texture pick a loaf with a chewy interior and sturdy crust
- Softened butter: Allows for an irresistibly crispy and golden exterior Room-temperature butter is easier to spread so let it warm up on the counter if possible
- Basil pesto: Use a high-quality pesto with bright green color and fresh basil aroma Homemade is great for the freshest flavor but select store-bought that lists olive oil and real basil near the top of the ingredients
- Mozzarella cheese: The king of meltability It blankets the bread in creamy strings of cheese Choose whole milk mozzarella for a richer taste
- Sharp cheddar cheese: Offers a punchy savory contrast to the mild mozzarella Look for aged cheddar for extra depth and tang
Step-by-Step Instructions
- Prep the Bread:
- Spread a generous layer of softened butter over one side of each bread slice On the other side spread basil pesto all the way to the edges for maximum flavor
- Build the Sandwich:
- Arrange mozzarella and cheddar slices in a single layer on the pesto side of two bread slices Place the remaining slices of bread on top with the buttered side facing out
- Grill the Sandwich:
- Set a nonstick skillet over medium heat Once hot lay the sandwiches in the pan Cook for about three to four minutes per side You want each side golden brown and the cheese inside completely melted If needed lower the heat slightly to avoid burning and ensure even melting
- Rest and Serve:
- Transfer the sandwiches to a cutting board and let them cool for a couple of minutes before slicing This resting time keeps the cheeses from oozing out and burning your fingers Serve on their own or dunked in hot tomato soup

One of my favorite parts of making this sandwich is watching the cheese bubble out the edges growing up we would rush to the kitchen to snag the first crispy bits sliced from the pan
Storage Tips
Store any leftovers wrapped tightly in foil or an airtight container at room temperature for a few hours or in the fridge overnight To reheat use a skillet over low heat This brings back the crispy crust better than the microwave ever could
Ingredient Substitutions
Swap in different cheeses for new flavors Provolone fontina or gouda are melty options For a vegan twist plant-based butters and cheese alternatives work surprisingly well You can try sun-dried tomato pesto for even more punch if basil is not your favorite
Serving Suggestions
Pair your pesto grilled cheese with a bowl of classic tomato soup for comfort food perfection It also makes a satisfying lunch with a simple salad or even as a snack cut into small triangles for sharing at parties
A Brief History
While grilled cheese has been comforting eaters for generations the addition of pesto comes from Italian influences Pesto from Genoa Italy was traditionally used for pasta but its bold flavor translates perfectly to this modern twist on a diner favorite
Frequently Asked Questions
- → What kind of bread is best for this?
Sourdough or Italian bread works best due to its sturdy texture and ability to hold up to the melted cheese and pesto.
- → Can I use different cheeses?
Absolutely! Provolone, fontina, or gouda are excellent alternatives for a unique flavor profile.
- → How can I make this spicier?
Add a pinch of red pepper flakes to the pesto for a delightful kick.
- → Is there a vegan version?
Yes! Substitute vegan butter, pesto, and cheese alternatives to create a plant-based version.
- → What's the secret to a crispy crust?
Brush the outside of the bread with mayonnaise instead of butter for an extra crispy and golden crust.
- → What goes well with this sandwich?
Tomato soup is a classic pairing! A simple side salad also complements the richness of the grilled cheese.