Cheeseburger Biscuit Bake

Featured in Hearty Main Courses.

Craving cheeseburgers? This easy casserole combines ground beef, cheese, and biscuits for a comforting, crowd-pleasing meal. Brown ground beef with onion and garlic, season with Worcestershire, ketchup, and mustard. Mix with biscuit pieces and cheese, then bake until golden brown. Garnish with lettuce, tomato, or pickles for that classic cheeseburger flavor.

Customize your bake! Try adding bacon, BBQ sauce, or taco seasoning for unique variations. Leftovers store well in the fridge or freezer. Serve warm with fries, salad, or onion rings.

Casey
Updated on Sat, 04 Oct 2025 12:23:44 GMT
A burger with lettuce and cheese on a plate. Pin it
A burger with lettuce and cheese on a plate. | cookingwithcasey.com

This Cheeseburger Biscuit Bake is my solution for those nights when the family craves a juicy cheeseburger but I need the simplicity of a one pan casserole. It delivers all the classic, savory flavors of a burger with fluffy biscuits baked right in, creating a comforting meal that’s become a weeknight hero in my kitchen.

I first made this for a last minute get together, and it was the first dish to completely disappear. Now my kids ask for it whenever their friends come over for dinner.

Ingredients

  • Ground beef: an 80/20 blend gives you the best flavor and juiciness
  • Medium onion: finely chopped to melt into the beef mixture
  • Garlic: provides a foundational aromatic flavor
  • Worcestershire sauce: adds a deep, savory umami kick that really makes it taste like a burger
  • Ketchup or tomato paste: for that classic tangy sweetness
  • Mustard: yellow or Dijon both work to add a little zest
  • Refrigerated biscuit dough: the canned kind is a huge time saver and bakes up perfectly fluffy
  • Shredded cheddar cheese: use a good quality sharp cheddar for the best melt and flavor
  • Diced pickles: optional but they add a fantastic briny crunch
  • Cooked bacon crumbles: for a bacon cheeseburger twist that is always a hit
  • Sesame seeds: sprinkled on top gives the illusion of a classic burger bun

Step by Step Instructions

Brown the Beef:
In a large skillet over medium high heat, cook the ground beef, using a spatula to break it into small crumbles. Continue cooking until it's fully browned, about 5 to 7 minutes. Be sure to drain off any excess grease from the pan before moving on. This step is key to avoiding a greasy casserole.
Sauté the Aromatics:
Add the finely chopped onion and minced garlic to the skillet with the beef. Cook for another 2 to 3 minutes, stirring frequently, until the onion becomes soft and translucent. This builds a delicious flavor base for the entire dish.
Season the Filling:
Stir the Worcestershire sauce, ketchup, mustard, salt, and pepper directly into the beef mixture. Let it simmer for a couple of minutes so all those classic burger flavors can meld together beautifully. Once it's fragrant, remove the skillet from the heat.
Combine the Casserole:
Open your can of refrigerated biscuits and carefully cut each one into four equal pieces, or quarters. In a large mixing bowl, combine the seasoned beef mixture, the biscuit pieces, and the shredded cheese. If you're using them, add the diced pickles and bacon crumbles now. Gently stir everything together until the biscuit pieces are evenly coated.
Assemble and Bake:
Grease a 9x13 inch baking dish and pour the entire mixture into it. Use a spatula to spread it into an even layer. Sprinkle a little extra shredded cheese and a good pinch of sesame seeds over the top. Bake in a preheated 375°F oven for 25 to 30 minutes. You're looking for the biscuits to be a deep golden brown and cooked all the way through.
Rest and Serve:
Let the casserole rest on the counter for about 5 minutes after it comes out of the oven. This helps it set up and makes it easier to serve. Garnish with fresh toppings like shredded lettuce or diced tomatoes and serve warm with your favorite burger sauces on the side.
A plate of food with a biscuit and meat on top. Pin it
A plate of food with a biscuit and meat on top. | cookingwithcasey.com

My absolute favorite ingredient here is the Worcestershire sauce. It adds a depth that ketchup and mustard alone just can't achieve. I remember my daughter, who claims she doesn't like onions, happily eating her second serving of this casserole. The finely chopped onions just melt into the sauce, adding flavor without any noticeable texture.

Storage and Reheating Tips

Storing leftovers is simple. Just let the casserole cool completely, then transfer it to an airtight container. It will keep well in the refrigerator for up to three days. For longer storage, you can freeze individual portions wrapped tightly in plastic wrap and then foil for up to two months. To reheat, I find the oven works best to revive the biscuits; just warm it at 350°F until heated through.

Ingredient Substitutions and Variations

Don't be afraid to make this recipe your own. You can easily swap the ground beef for ground turkey or even plant based crumbles for a lighter version. Any good melting cheese will work beautifully, so feel free to try pepper jack for a spicy kick or a Swiss and mushroom combination. I've also snuck in finely diced bell peppers and mushrooms with the onions for an extra serving of veggies.

Serving Suggestions

While this casserole is a complete meal on its own, it pairs wonderfully with classic burger side dishes. A crisp, simple green salad with a vinaigrette offers a fresh contrast. You can also go all out with a side of crispy french fries, tater tots, or onion rings. For a true cookout feel, a scoop of creamy coleslaw on the side is always a great choice.

Frequently Asked Questions

→ Can I use a different type of cheese?

Absolutely! Pepper jack adds spice, Swiss offers richness, and Monterey Jack creates a milder flavor. Experiment and find your favorite cheese blend!

→ What's the best way to prevent the biscuits from getting soggy?

Don't overmix the biscuit pieces with the beef mixture. Also, make sure the beef is drained well to prevent excess moisture in the casserole.

→ Can I use ground turkey or chicken instead of beef?

Yes, you can! Use lean ground turkey or chicken for a healthier option. Make sure to adjust seasoning as needed to complement the different flavor profiles.

→ How do I make a breakfast version of this bake?

Add scrambled eggs and breakfast sausage along with the cheese and beef mixture before baking. Consider using sharp cheddar for extra flavor in the morning!

→ What are some good toppings to add after baking?

Fresh shredded lettuce, diced tomatoes, pickles, and a drizzle of your favorite burger sauce are all fantastic options. You can also add a dollop of sour cream or guacamole for a Tex-Mex twist.

→ How can I make sure the biscuits are cooked through?

Check the biscuit pieces in the center of the casserole. They should be golden brown and fully cooked. If the top is browning too quickly, cover the casserole loosely with foil during the last few minutes of baking.

Cheeseburger Biscuit Bake Casserole

Quick cheeseburger casserole with beef, cheese, and biscuits. Ready in under an hour, a comforting and satisfying meal.

Prep Time
15 Minutes
Cook Time
30 Minutes
Total Time
45 Minutes
By: Casey

Category: Hearty Main Dishes

Difficulty: Easy

Cuisine: American

Yield: 8 Servings

Dietary: ~

Ingredients

→ Main Components

01 680g ground beef (80/20 lean)
02 1 medium onion, finely diced
03 2 cloves garlic, minced
04 15ml Worcestershire sauce
05 15ml ketchup or tomato paste
06 5ml mustard (yellow or Dijon)
07 Salt and black pepper, to taste
08 1 can (450g) refrigerated biscuit dough (8 large biscuits)
09 250g shredded cheddar cheese (or a blend of cheddar and mozzarella)

→ Optional Additions

10 75g diced pickles
11 60g cooked bacon crumbles

→ Garnish

12 Additional shredded cheese
13 Sesame seeds
14 Fresh shredded lettuce, tomato slices, or additional pickles (for serving)

Instructions

Step 01

Preheat oven to 190°C (375°F). In a large skillet, brown ground beef over medium-high heat, breaking it apart with a spatula. Drain any excess fat from the skillet.

Step 02

Add diced onion and minced garlic to the skillet; sauté for 2 to 3 minutes until softened. Stir in Worcestershire sauce, ketchup, mustard, salt, and pepper. Simmer for 2 to 3 minutes, then remove from heat.

Step 03

Quarter each biscuit from the can.

Step 04

In a large mixing bowl, combine the beef mixture, quartered biscuit pieces, shredded cheese, and any optional diced pickles or bacon crumbles. Mix thoroughly to ensure even distribution.

Step 05

Transfer the mixture into a greased 23x33cm (9x13-inch) baking dish, spreading it evenly. Generously sprinkle additional shredded cheese and sesame seeds over the top.

Step 06

Bake uncovered for 25 to 30 minutes, or until the biscuits are golden brown and thoroughly cooked. If the top begins to brown excessively, cover loosely with aluminium foil.

Step 07

Allow the casserole to rest for 5 minutes before serving. Garnish with fresh shredded lettuce, diced tomatoes, or additional pickles for an authentic cheeseburger experience. Serve warm, accompanied by ketchup, mustard, or your preferred burger sauce.

Notes

  1. Ensure biscuit pieces in the center are fully baked before removing from the oven.
  2. For cheese variations, try pepper jack for a spicier kick, or Swiss for a richer flavor profile.
  3. Consider healthier swaps by using lean ground turkey or chicken and reduced-fat cheese.
  4. Enhance nutritional value by mixing in sautéed mushrooms, peppers, or spinach.
  5. Achieve a crispy finish by broiling for 1 to 2 minutes at the end to perfectly brown the top.
  6. For a Bacon Cheeseburger Bake, incorporate crumbled bacon into the beef mixture and top with more before baking.
  7. Create a BBQ Cheeseburger Bake by replacing ketchup with your favorite barbecue sauce for smoky sweetness.
  8. Transform into a Tex-Mex Cheeseburger Bake by using taco seasoning in the beef, adding jalapeños, and topping with salsa and sour cream after baking.
  9. Replicate a Big Mac Style Bake by adding shredded lettuce, diced pickles, and Thousand Island dressing after baking.
  10. For a Breakfast Cheeseburger Bake, add scrambled eggs and breakfast sausage along with the cheese and bake as usual.
  11. Store leftover portions in an airtight container in the refrigerator for up to 3 days.
  12. For longer storage, wrap individual portions tightly in foil or plastic wrap and freeze for up to 2 months.
  13. Reheat in the oven at 175°C (350°F) for 10 to 15 minutes, or in the microwave for 1 to 2 minutes.
  14. Excellent serving suggestions include pairing with crispy French fries, a fresh garden salad, onion rings, or coleslaw.

Tools You'll Need

  • Large skillet
  • Spatula
  • Large mixing bowl
  • 23x33cm (9x13-inch) baking dish

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Dairy
  • Gluten
  • Beef

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 480
  • Total Fat: 28 g
  • Total Carbohydrate: 28 g
  • Protein: 26 g